When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...

HOUSTON – (Aug. 9, 2022) – Knowing the structure of a complex biological system isn’t nearly enough to understand how it works. It helps to know how the system moves. In that light, Rice University ...

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

Researchers have modeled a key mechanism by which DNA replicates. The study could help identify new targets to treat disease. Knowing the structure of a complex biological system isn't nearly enough ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

The Nobel prize in chemistry has gone to research showing how DNA fixes the damage that can cause cancer and premature ageing. Tomas Lindahl of the Francis Crick Institute in Hertfordshire, UK, Paul ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.