SNP, which stands for Single Nucleotide Polymorphism, is a DNA sequence variation that occurs commonly within a population. This new array, called the "Japonica Array," covers the whole-genome region ...

A research group, led by Professor Masao Nagasaki and Senior Assistant Professor Yosuke Kawai at Tohoku University Tohoku Medical Megabank Organization, has successfully designed the first ever SNP*1 ...

The aim of the present work was to study the prevalence and nature of pathogenic array findings and to evaluate the diagnostic value of prenatal genomic array testing in a large cohort of fetuses with ...

Objective: Our goal was to evaluate the influence of quality control (QC) decisions using two genotype calling algorithms, CRLMM and Birdseed, designed for the Affymetrix SNP Array 6.0. Methods: ...

PAM50 intrinsic subtyping and pathologic responses to neoadjuvant trastuzumab-based chemotherapy in HER2-positive breast cancer. Background: Early detection and monitoring the progress of common ...

Single nucleotide polymorphisms (SNPs) are sequence variants in which two alternate bases occur at one position. The SNP Consortium is developing a dense map of SNPs in the hope that certain variants ...

A phase I, open-label, dose-escalation study to evaluate the safety, pharmacokinetics, and pharmacodynamics of oral azacitidine in subjects with myelodysplastic syndromes (MDS) or acute myelogenous ...

Affymetrix, Inc. has announced that it has released a data set based on extensive validation of novel SNPs from the 1000 Genomes Project. This data will give researchers access to more rare mutations ...

Using SNP-CGH to Profile for Amplifications, Duplications, and Deletions The beginnings of personalized medicine have been forged by recent advances in SNP genotyping technologies. It is now possible ...

Expert Rev Proteomics. 2007;4(6):741-756. The combined use of microarrays, CGH and SNP arrays in cancer will probably prove important in uncovering more specific tumor and host prognostic and ...