New findings indicate that transfer RNA (tRNA) has another function in addition to its long-established role in gene expression. tRNA also helps control apoptosis, or programmed cell death, according ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

Mycoplasma leucyl-tRNA synthetases (LeuRSs) have been identified in which the connective polypeptide 1 (CP1) amino acid editing domain that clears mischarged tRNAs are missing (Mycoplasma mobile) or ...

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Rensselaer Polytechnic Institute's ...

The research group led by Professor Tsutomu Suzuki of The University of Tokyo is opening new horizons in RNA modification research. In particular, the group has discovered a reversible RNA ...

Boston, Massachusetts--(Newsfile Corp. - April 29, 2025) - Tevard Biosciences, Inc., a privately held biotechnology company pioneering tRNA-based therapies to cure a broad range of genetic diseases, ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 18 (May 3, 2016), pp. 4994-4999 (6 pages) During translation, a plethora of protein factors bind to the ...