Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company’s CRISPR-based ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

EVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant ...

Cells frequently encounter conditions that can damage them or even lead to cell death. To keep functioning, they must rapidly ...

Researchers have identified a stress-activated control mechanism that helps breast cancer cells reshape gene activity to ...

This article examines some of the cell-based approaches that researchers are using to study acquired drug resistance and the ...

Multicellular cyanobacteria do something strikingly sophisticated with their DNA, toggling key genes on and off as day turns to night so different cells can specialize without starving the colony of ...

The FDA is said to be making a U-turn on uniQure’s one-time gene therapy candidate for Huntington’s disease despite the treatment being hailed as a game changer. The FDA no longer agrees that data ...

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through ...

A hormone-free pill, called YCT-529, that temporarily stops sperm production by blocking a vitamin A metabolite has just concluded its first safety trial in humans, getting a step closer to increasing ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mycobacterium tuberculosis causes long-term ...